The 2017 Center for Global Regulatory Cooperation Good Regulatory Design document9 is the first comprehensive compilation of global Regulatory Coherence principles and policies devel- oped to serve as a guide for governments interested in better understanding and implementing fundamental whole-of-government regulatory coherence policies. The guide is written for senior policy makers at the highest level of government responsible for increasing the efficiency of the state and includes definitions of the key elements and a policy implementation checklist. Several Regulatory Coherence and GRP tools have been developed: The World Health Organization (WHO) Good Regulatory Practices Guidelines for National Regulatory Authorities for Medical Products, currently in draft form, seeks to: respond to requests from Member States for guidance on how to develop legal frameworks; serve as a foundational document that applies internationally accepted principles of GRP to the regulation of medical products; and apply to the establishment of new regulatory systems and the updating of existing ones. Principles of GRP, according to the draft WHO Guidelines, include: • Legality • Impartiality • Consistency • Proportionality • Flexibility • Effectiveness • Efficiency • Clarity • Transparency Implementing GRP, according to the draft WHO Guidelines, includes: • Conducting Regulatory Impact Analysis •  Compliance and enforcement (should be clear, proportionate and achievable) •  Consultation (at the center of an effective regulatory system) •  Forward looking regulatory agenda (identifies priorities in management of regulations) •  Monitoring and evaluation (verifying that regulatory intervention achieved its goal) •  Management of the regulatory stock (periodic review of all regulations to mitigate redundancies, inconsistencies and outdated instruments) 9 THE 2005 APEC-OECD INTEGRATED CHECKLIST ON REGULATORY REFORM LAYS OUT A VOLUNTARY GRP FRAMEWORK FOR SELF-ASSESSMENT THAT INCLUDES REGULATORY POLICIES. Necessary elements of Regulatory Coherence which comprise such policies include: A) Transparency & Stakeholder Involvement • Regulatory Forecast • National Regulatory Register • Notification and Public Comment • Publication of Evidence/Regulatory Analysis • Respond to Stakeholder Input • Quality Data & Sound Science B) Risk Based Approach C) Regulatory Impact Assessment (RIA) D) Pro-Competitive Analysis E) International Impact F) Use of International Standards G) Ex-post Assessment H)  Central Regulatory Review, including establishment of a central regulatory oversight body 9 https://standardsalliance.ansi.org/Project-for-the-Medical-Device-Sector.aspx