Page 1 Page 2 Page 3 Page 4 Page 5 Page 6 Page 7 Page 8 Page 9 Page 10 Page 11 Page 12 Page 13 Page 14 Page 15 Page 16 Page 17 Page 18 Page 19 Page 20 Page 21 Page 22 Page 23 Page 24 Page 25 Page 26 Page 27 Page 28 Page 29 Page 30 Page 31 Page 32THE IMPORTANCE OF DIAGNOSTIC TESTS IN FIGHTING INFECTIOUS DISEASES Infectious diseases are caused by pathogenic microorganisms, such as bacteria, viruses, parasites or fungi, and each year millions of Americans are affected by them.1 Many infectious diseases have minor complications if diagnosed and treated appropriately. But left untreated, others—including pneumonia, tuberculosis, HIV and meningitis—can be life-threatening. 2 New bacteria, viruses, fungi and parasites emerge and evolve each year.3 Densely populated regions and easy travel accelerate the spread of infectious disease. 4 Antibiotic resistance is a major global health concern. More than 2 million Americans develop drug-resistant infections each year.5 Human papillomavirus is linked to cervical cancer. Helicobacter pylori is linked to stomach cancer and peptic ulcers. Hepatitis B and C are linked to liver cancer. Early and accurate diagnosis of infectious disease is critically important because: Diagnosis can improve the effectiveness of treatments and avoid long-term complications for the infected patient.7 Undiagnosed patients can unknowingly transmit the disease to others. Early diagnosis can help to prevent or stop an outbreak.8 Widespread overuse and misuse of antibiotics contribute to antibiotic resistance. Diagnostic tests can determine when antibiotics are an appropriate treatment—and when they are not.9 Test manufacturers are continually advancing and developing diagnostics to match the evolution and emergence of new infectious diseases. Recent advances enable health care providers to reach a diagnosis more quickly, improving patient outcomes and lowering associated health care costs. Infectious diseases were associated with an economic burden of more than $120 billion in the U.S. in 2014 alone. 10 Use of a diagnostic test for the early detection of MRSA enabled doctors to prescribe optimum antibiotics 1.7 days sooner, reducing the length of hospital stays by 6.2 days and lowering hospital costs by more than $21,000. 11 Point of care (POC) testing allows patient diagnoses in the physician’s office, an ambulance, the home, the field or in the hospital. The results allow for rapid treatment.12 During the recent Ebola crisis, test manufacturers rushed to develop new POC rapid diagnostic tests to avoid multi-day delays in diagnosing affected patients. Between November 2014 and December 2015, four such tests were developed and approved by the World Health Organization; the U.S. Food and Drug Administration has authorized 10 tests for emergency use. Had these POC tests been used during the epidemic, researchers estimate that the scale of the epidemic could have been reduced by more than a third.13 Infectious diseases pose a greater challenge today than they did even two decades ago. A few types of infections have been linked to a long-term increased risk of cancer:6 employment in the medtech industry and our commitment to working with veterans to facilitate their transition to the private sector following military service. AdvaMed also launched a digital advertising campaign to amplify our message to the health policy community about the long-term value and improved health outcomes that life-changing innovation provides. These ads created over 7.5 million impressions and drove significant traffic back to our LCI campaign website. Impact data showed that audiences exposed to the ads generally viewed the value of medical technology 10 percent more favorably than those not exposed to the ads. Kim Beer, director of public policy at the Susan G. Komen organization, addresses a Capitol Hill briefing in December on the value of radiotherapy for cancer care, alongside fellow panelists Joshua Levine of Accuray and David Beyer, chair of the American Society for Radiation Oncology (at right). Georgia Congressman Tom Price (center) visits Elekta facilities outside Atlanta in August for an event co-hosted by AdvaMed to promote military veteran employment in the medtech industry, along with (from left to right) Dunwoody Mayor Denis Shortal; AdvaMed’s Scott Whitaker; JC Glick, partner at Kenning Associates; and Bill Yaeger, Elekta’s executive vice president, North America region. 17